Thanks for the replies about KSP everyone, and thanks Zakalawe for your answer about F1. It rather pole-axes the idea I had.
A couple weeks ago I happened across an article about the early days of the Space Shuttle design, and it mentioned something called "Saturn-Shuttle", in which a modified S1-C booster would be used to launch the shuttle orbiter.. The configuration was booster + the orbiter's fuel tank on top with the Orbiter itself on the side.
With all these successful landings of Stage 1 boosters and talk of Big F.... Rockets from SpaceX, it got me to thinking how feasible it would be to launch the Shuttle Orbiter on top of a hugely modified S1-C stage. The stack would be as follows.
1. The modified version of the S1-C (call it S9-A) would be much wider and taller, with nine F1 engines (eight in an octaweb configuration and one in the centre a la Falcon 9)
2. The Shuttle Orbiter would be parked on top of the S9-A, with an interstage faring.
3. The Orbiter would be modified with a shorter payload bay, the saved space becoming additional fuel tanks for the final kick into orbit.
The plan would be two-stage to orbit, with the S9-A Stage 1 recovered back to the Cape using the single centre F1 engine for boostback, reentry and landing burns, and Stage 2 being the Orbiter itself. My plan is rather foiled by the fact that an F1 engine cannot be relit so a different centre engine would have to be used (F1B perhaps... can that be relit?)
The Orbiter + payload + on board fuel weighs 230,000.
Nine F1 engines will deliver 13.5 million pounds of thrust, so it was a matter of working out how heavy a fully-fuelled S9-A would be. I don't think I'd have any trouble getting it off the ground, but I have an idea velocity might be a problem, with the Orbiter carrying so little fuel, Stage 1 might have to be going so fast that it could not be recovered, and the stack structure would have to be enormously strong to withstand MaxQ.
I thought I might be able to experiment with it in KSP, but that is sounding like it won't be straightforward.
Anyway, it was just a thought.......