Regarding '60s vs current tech, there is one example where old was clearly superior (in one aspect). I'm referring to computer memory.
Modern solid-state memory is susceptible to radiation damage, and the problem is getting worse as semiconductor geometries and power supply voltages continue to shrink and densities rise. A cosmic ray hit can flip the state of a memory bit or (with high enough energy) completely destroy it. With ever-smaller geometries, a single CR hit can damage more elements (though smaller chip areas reduce the odds of a hit somewhat). Core memory was virtually immune to radiation damage.
This problem can be mitigated by using larger geometries (at the expense of some efficiency, size, and weight) and by implementing redundancy, error detection/correction, and remapping techniques (to disable damaged areas of memory). Still, it's a very real issue that has to be addressed in all spacecraft designs. I heard (some time back) that it was getting harder for designers to find rad-tolerant memories as more semiconductor fabs migrate to smaller-geometry processes.